ScienceON 검색
ScienceON '특허' 검색
더보기No | 제목 / 내용 |
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1 |
USE OF THE SALMONELLA SPP TYPE III SECRETION PROTEINS AS A PROTECTIVE VACCINATION / UNIV OKLAHOMA STATE Salmonella enteric serotype Typhimurium is a causative agent for gastroenteritis. It is the leading cause of hospitalization and death caused by a food-borne pathogen in the US. As is the case with many gram- negative pathogens, Salmonella spp. use type III secretion systems (T3SS) to deliver proteins to host cells to induce infections. The T3SS uses a molecular syringe and needle, the type III secretion apparatus (T3SA), as a conduit for the transport of the T3SS proteins from the bacteria to the host. Because proteins associated with the tip of the T3SA are extracellular, they are potential protective subunit vaccine candidates against Salmonella. These pathogens also have a T3SS that is involved with intracellular escape from the vacuole with an associated T3SA. Within this invention, we begin to show proof of concept that these proteins are protective. |
2 |
USE OF THE SALMONELLA SPP TYPE III SECRETION PROTEINS AS A PROTECTIVE VACCINATION / The Board of Regents for Oklahoma State University Salmonella enteric serotype Typhimurium is a causative agent for gastroenteritis. It is the leading cause of hospitalization and death caused by a food-borne pathogen in the US. As is the case with many gram- negative pathogens, Salmonella spp. use type III secretion systems (T3SS) to deliver proteins to host cells to induce infections. The T3SS uses a molecular syringe and needle, the type III secretion apparatus (T3SA), as a conduit for the transport of the T3SS proteins from the bacteria to the host. Because proteins associated with the tip of the T3SA are extracellular, they are potential protective subunit vaccine candidates against Salmonella. These pathogens also have a T3SS that is involved with intracellular escape from the vacuole with an associated T3SA. Within this invention, we begin to show proof of concept that these proteins are protective. |
ScienceON '논문' 검색
더보기ScienceON '보고서' 검색
더보기No | 제목 / 내용 |
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1 |
활성산소종에 의한 세포의 성장, 분화, 및 사멸의 조절기전 민도식 , 카톨릭대학교 , 2002 |
2 |
신경아교세포의 활성조절 및 사멸조절을 통한 뇌질환 치료방향의 모색: 분비된 사이토카인을 통한 세포들의 상호관계 및 그 효과에 관한 연구 이경진 , 아주대학교 , 2003 |