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국가과학기술정보센터(ScienceON) 특허검색
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1 COMPATIBLE SOLUTES FOR PREVENTING OR TREATING SARS-COV-2 INFECTIONS / BITOP AG
The present invention relates to the use of organic and highly water-soluble compatible solutes or of a solute mixture, preferably in the form of an inhalable composition suitable for oropharyngeal, nasal and intravenous administration, in the prevention or treatment of diseases caused by ss(+)RNA viruses of the Coronaviridae family, preferably diseases caused by SARS-CoV-1, SARS-CoV-2, MERS-CoV, HCoV-HKU1, HCoV-OC43, HCoV-NL63 and/or HCoV-229E. Particularly suitable solutes according to the invention are ectoine and its derivatives, glycoin, mannosylglycerate (firoin) and mannosylglyceramide (firoin-A), which, by virtue of their strong water-binding capacity, reduce the binding of the viruses to the receptors of the host cell in the transitional epithelium, e.g. eye, in the inner epithelium, e.g. lung, and in the endothelium and thus reduce or prevent the reproduction of the virus. According to the invention, prevention is made possible by sputum and breath which are less infectious, and treatment and rehabilitation of the affected tissues are made possible by the membrane-protecting properties of the compatible solutes according to the invention.
2 COMPATIBLE SOLUTES FOR PREVENTING OR TREATING SARS-COV-2 INFECTIONS / bitop AG
The present invention relates to the use of organic and highly water-soluble compatible solutes or a solute mixture, preferably in the form of an inhalable, oropharyngeally, nasally and intravenously administrable composition, in the prevention or treatment of diseases caused by ss(+)RNA viruses of the Coronavriridae family, preferably of those diseases caused by SARS-CoV-1, SARS-CoV-2, MERS-CoV, HCoV-HKU1, HCoV-OC43, HCoV-NL63 and/or HCoV-229E. Particularly suitable solutes in the meaning of the invention are ectoine and its derivatives, Glycoin, mannosylglycerate (Firoin) and mannosylglyceramide (Firoin-A), which, due to their strong water-binding capacity, reduce the binding of the viruses to the receptors of the host cell in the transitional epithelium, e.g. eye, in the internal epithelium, e.g. lung, and in the endothelium and thus reduce or prevent the multiplication of the viruses. According to the invention, prevention is enabled by a reduced infectious sputum and breath, and treatment and rehabilitation of the affected tissues is enabled by the membrane protective properties of the compatible solutes according to the invention.

ScienceON '논문' 검색

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ScienceON 논문 검색
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1 Arthrofibrosis after ACL Reconstruction and Accelerated Rehabilitation (SS-39)
, 2005 ; Vol. 21 , Issue 6
2 1-1-SS2-3 Rehabilitation for the disaster survivors
, 2012 ; Vol. 2012 , Issue 6
3 SS5-2 URBAN STREAM REHABILITATION - LESSONS (TO BE) LEARNED FROM URBEM PROJECT
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2005 ; Vol. 31 , Issue 2
4 Accelerated Rehabilitation After Arthroscopic Bankart Repair: A Prospective Randomized Clinical Study (SS-16)
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2002 ; Vol. 18 , Issue 5
5 Does Slower Rehabilitation After Arthroscopic Rotator Cuff Repair Lead to Stiffness? (SS-22)
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2007 ; Vol. 23 , Issue 6
6 SS5-2 URBAN STREAM REHABILITATION - LESSONS (TO BE) LEARNED FROM URBEM PROJECT
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2005 ; Vol. 2005 , Issue 6
7 Acute Achilles Tendon Repair Using a Mini-Dorsolateral Incision and Accelerated Rehabilitation (SS-51)
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2010 ; Vol. 26 , Issue 6
8 Brostrom Lateral Ankle Reconstruction with Concurrent Ankle Arthroscopically and an Accelerated Rehabilitation Program (SS-63)
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2009 ; Vol. 25 , Issue 6
9 Revision ACL Reconstruction with Nonirradiated Patellar Allograft Using Immediate Weightbearing and an Accelerated Rehabilitation Program (SS-02)
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2003 ; Vol. 19 , Issue 5
10 Early Versus Delayed Rehabilitation in Arthroscopic Rotator Cuff Surgery: A Dual Surgeon Comparative Cohort Study (SS-15)
LOCAL ORGANIZING COMMITTEE OF THE XXV CONGRESS , 2012 ; Vol. 28 , Issue 6

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